Friday, January 1, 2010

Will vitamin D stop the new killer strain of drug-resistant tuberculosis, or is sunlight the cure?

***
It appears that the first case of drug-resistant TB has arrived in the US from Peru.[1] It is nearly 100% resistant to antibiotics, and does not bode well for the country, since it could cause an immense killer epidemic. There seems to be no answer to the “superbug” that causes it. Or is there an answer? Could sunlight and its skin-produced hormone, vitamin D, provide answers to this latest health threat?

Sunlight has a long history of treatment for tuberculosis. Much of the following discussion of TB comes from Dr. Fielder’s history of heliotherapy.[2]

As early as 1857 Madame Duhamel of France exposed children with TB to sunshine because it hastened their recovery. Many doctors of that same era used heliotherapy (sunlight treatments) with great success, and as Dr. Fielder states, “As a general rule, the experience of all the Hygienists in their use of sunbathing was so successful that all question of doubt as to its place in the Hygienic System was ensured.”

Madame Duhamel was correct about sunbathing healing tuberculosis (TB). Later on, a disillusioned physician, Dr. Rollier, gave up a promising surgical practice and moved to the mountains of the Swiss countryside to practice medicine there. However, he discovered that the people needed little help, as they were seldom sick. People were always telling him, “Where the sun is, the doctor ain’t [sic].” In fact, Dr. Rollier’s fiancĂ©e had TB and would have died without intervention. He brought her to the Alpine area, exposed her regularly to sunshine, and she completely recovered.

Dr. Rollier opened a sanatorium in 1903 that was really just an extremely large solarium (sunbathing facility) with patient living quarters. There were 2,167 patients under Dr. Rollier’s care for TB following World War One. Of these, 1,746 completely recovered their health. Only those in the most advanced stages of the disease failed to recover.

In 1895, Dr. Niels Finsen made use of the first artificial UV light in treating patients with a particularly virulent form of TB known as lupus vulgaris (a skin disease). Though the disease was considered incurable, 41 of every 100 patients under his care recovered. Finsen’s work earned the Nobel Prize in medicine in 1903.

These researchers and physicians were not alone in their observations of the therapeutic power of sunlight. In 1877 two scientists, Arthur Downes and Thomas Blunt, discovered that sunlight was bactericidal. In 1890, the German microbiologist Robert Koch (who had isolated and described the tuberculosis bacterium in 1882), showed that sunlight killed TB bacteria.[3]

Recently, the interest in Vitamin D to thwart TB is being revisited.[4] [5] [6] and it has been shown that Black immigrants to Australia have much lower vitamin D levels than the general population and a much higher risk of TB.[7] Moreover, the effectiveness of vitamin D was demonstrated against the TB bacteria in an experiment in which a single dose of vitamin D (100,000 IU) significantly increased immunity to the TB bacterium.[8] The effectiveness of vitamin D against TB is determined by the production of cathelicidin,[9] an antibacterial peptide, which we could call the “body’s natural antibiotic.”

Further corroborating vitamin D’s essential role is that people who lack vitamin D receptors (VDR) are three times more likely to contract TB as those with normal VDR.[10] Vitamin D also inhibits the body’s inflammatory response to TB infection in the lungs.[11] [12] Considering the efficacy of sunlight therapy and vitamin D in inhibiting or even curing tuberculosis, doesn’t it seem that it’s time to return to the sun? Remember that you should never burn yourself in the sunlight.

[1] http://www.sphere.com/nation/article/first-case-of-highly-drug-resistant-tuberculosis-in-us/19294836?icid=mainhtmlws-main-ndl1link3http%3A%2F%2Fwww.sphere.com%2Fnation%2Farticle%2Ffirst-case-of-highly-drug-resistant-tuberculosis-in-us%2F19294836
[2] Fielder, J. Heliotherapy: the principles & practice of sunbathing. Soil and Health Library (online) http://www.soilandhealth.org/index.html.
[3] Hobday, R. The Healing sun. Findhorn Press 1999:132
[4] Martineau, A. Effect of vitamin D supplementation on anti-mycobacterial immunity: a double-blind randomized placebo-controlled trial in London tuberculosis contacts. Int J Tuberculosis Lung Dis 2005;9:S173.
[5] Martineau, A. et al. Vitamin D status of tuberculosis patients and healthy blood donors in Samara City, Russia. Int J Tuberculosis Lung Dis 2005;9:S225.
[6] Nnoaham, K. et al. Low serum vitamin D levels and tuberculosis: a systematic review and meta-analysis. Int J Epidemiol 2008;37:113-19.
[7]Gibney, K. et al. vitamin D deficiency is associated with tuberculosis and latent tuberculosis infection in immigrants from sub-Saharan Africa. Clin Infect Dis 2008’46:443-46.
[8]Martineau, A et al. A single dose of vitamin D enhances immunity of mycobacteria. A J Respir Crit Care Med 2007;176:208-13.
[9]Liu, P. et al. vitamin D mediated human antimicrobial activity against mycobacterium tuberculosis is dependent on the induction of cathelicidin. J Immunol 2007;179:2060-63.
[10]Liu, W. et al. A case-control study on the vitamin D receptor gene polymorphisms and susceptibility to pulmonary tuberculosis. Zhonghua Liu Xing Bing Xue Za Zhi 2003;24:389-92.
[11] Selvaraj, P et al. Regulatory role of promoter and 3’ UTR variants of vitamin D receptor gene on cytokine response in pulmonary tuberculosis. J Clin Immunol 2008; January 30. Epub ahead of print.
[12]Vidyarani, M. et al. 1, 25 Hydroxyvitamin D3 modulated cytokine response in pulmonary tuberculosis. Cytokine 2007;40:128-34.

Monday, December 21, 2009

Do 250,000 North American babies die each year due to vitamin D deficiency?

Recent evidence has shown that pregnant mothers who were given 4,000 IU (ten times the usual dose) of vitamin D daily had only half the risk of giving birth to premature babies as those who were not supplemented. [1]

The importance of this information is shown in the fact that annually, half of all premature babies die in the first month after birth, according to the March of Dimes.[2] In North America, about 500,000 premature births occur annually.[2] If vitamin D supplementation could prevent half of these deaths, that would save the lives of 250,000 babies per year. Worldwide, the lives saved might be as many as 7 million, since approximately 13 million babies are born prematurely each year.

Premature babies, of course, are also low-birth-weight babies in most cases, which present an additional problem. Here is one more reason for mothers to get back in the sunlight: the potential for low birth weight in their babies.

Low birth weight is associated with poor mood, anxiety, depression, high blood pressure and other problems during childhood and afterward. Recent research shows that low birth weight is related to exposure by pregnant women to winter temperatures during a critical developmental time for the fetus.[3] [4] This could indicate vitamin D deficiency of the pregnant mother during “vitamin D winter,” the time of year in northern latitudes when the sun is too low in the sky to produce vitamin D. The answer, of course, is to use a tanning bed or take vitamin D3 supplements (3,000-5,000 IU) during the winter. Remember never to burn!

Those who make a living frightening people out of the sunlight are responsible for much of the vitamin D deficiency in the population of North America. Don’t expect them to change. Non-burning sunlight is a wonderful gift for health, and we must stop the insanity that is causing vitamin D deficiency. The child needs every possible advantage prior to birth, and one of the advantages is a mom with high vitamin D levels. The only source of vitamin D for the fetus is the mother’s body.

[1] Hollis, B. and Wagner C. Report from an international conference on vitamin D in Bruges, Belgium.
[2] March of Dimes statement Oct 4, 2009, based on World Health Organization (WHO) statistics.
[3] [1] Elter K, et al. Exposure to low outdoor temperature in the midtrimester is associated with low birth weight. Aust N Z J Obstet Gynecol 2004;44:553-7.
[4] Murray, L. et al. Links of Season and outdoor ambient temperature: effects on birth weight. Obstet Gynecol. 2000 Nov;96(5 Pt 1):689-95.

Monday, December 14, 2009

Melanoma: Midsummer Night’s Dream or Vitamin D-Deficiency Nightmare?

One of the most interesting medical research papers to arrive in recent memory is a 2009 study reported in the British Journal of Dermatology entitled, “Melanoma epidemic: a midsummer night’s dream?” [1] In it the authors make the case that melanoma is not caused by sunlight, but rather by an increasing diagnosis of benign lesions as melanoma. In other words, small spots on the skin that are harmless, and that in the past would have been classified as benign, are now being called stage-one melanoma. The authors point out that new diagnoses of stage-one melanoma have increased dramatically over the past few years, but new diagnoses of stage-two, -three and -four melanomas have not increased at all.

Some have suggested that the lack of increase in the latter stages of Melanoma is due to quick removal of the type-one melanomas, which prevents their progression to full-blown cancers. However, the authors point out that those in the study with type-two, three and four melanomas had not been previously diagnosed with type-one, and therefore could not have been “saved” by removal of type-one; the advanced cases were new presentations--people who had not been previously diagnosed with any stage of melanoma.

The case of these dermatologists—that melanoma is a “midsummer night’s dream”—is compelling. Obviously, millions of people who had nothing more than harmless lesions have been diagnosed with melanoma and have had their lesions removed surgically.

The researchers ended their analysis with this statement: “These findings should lead to a reconsideration of the treatment of ‘early’ lesions, a search for better diagnostic methods to distinguish them from truly malignant melanomas, re-evaluation of the role of ultraviolet radiation and recommendations for protection from it, as well as the need for a new direction in the search for the cause of melanoma.”

I can only say “amen” to this conclusion. However, these are not the first dermatologists to question the “epidemic” of melanoma and deny that sunlight is the cause. Dr. Bernard Ackerman, a celebrated dermatologist, wrote a monograph of several hundred pages entitled, Sunlight and the “Epidemic’ of Melanoma, Myth on Myth, in which he made the same argument about the supposed melanoma epidemic being due to incorrect diagnoses.[2] Dr. Arthur Rhodes, another dermatologist, has also given examples of many people who have died with real melanoma that occurred on areas of the body that were never exposed to sunlight.[3] These unfortunate people, believing that the lesions they discovered could not be melanoma because there was no sun exposure, failed to get help until it was too late.

Meanwhile, the world becomes more and more deficient in vitamin D due to the efforts of the “sunscare” movement that would have us believe that sunlight, one of God’s greatest gifts to living beings, is public enemy number one. This has resulted in incredible rates of vitamin D deficiency which have further resulted in an increase in at least 18 major cancers including breast, prostate and colon cancers. It has also resulted in increasing rates of heart disease, infections including flu, autism, and numerous other maladies that I discuss and fully document in my book. Never has there been a greater fraud than the push to scare people out of the sun to avoid a disease—melanoma—that is not an epidemic at all, and whose risk is increased by sun avoidance. Non-burning sunlight exposure is absolutely necessary for optimal human health.

Not only is the “epidemic” of melanoma a midsummer night’s dream, it has become a vitamin D-deficiency nightmare.

[1] N.J. Levell, C.C. Beattie,* S. Shuster and D.C. Greenberg* Melanoma epidemic: a midsummer night’s dream? British Journal of Dermatology 2009;161:630–634
[2] Ackerman, A. Sun and the “Epidemic” of Melanoma, Myth on Myth. Ardor Scribendi, LTD, New York, 2008
[3] Rhodes, A. Guest editorial, Melanoma’s Public Message. Skin and Allergy News 2003;34:1-4

Tuesday, May 12, 2009

Will vitamin D help the U.S. dominate the 2012 Olympics?

Vitamin D may indeed help the U.S. dominate the next summer Olympics. So says an online article at http://www.postchronicle.com/news/original/article_212229302.shtml

The article cites a new scientific paper, of which I was a coauthor(1), that presents compelling evidence that optimal vitamin D levels, produced by exposure to sunlight or sunlamps, dramatically improves strength, reaction time and endurance while profoundly reducing athletic injuries. It also increases the number and size of fast-twitch muscle fibers.

Most athletes, particularly winter athletes, are very low in vitamin D levels. When there is a correction of that deficiency, performance improves and injuries subside.

I have tried to get this information to the Utah Jazz for more than two years, but have not been able to get an appointment. The Jazz had more injuries than any team I have ever seen and still managed to make the playoffs. Their coaching is superb; no one is better than Jerry Sloan. But their listless play on the road and their incredible injury count screams that the team is vitamin D deficient. So, we might also have a headline that says, "Vitamin D may help the Utah Jazz (or some other struggling team) win the NBA championship in 2010." I will continue to try to find a team that will listen. Interested parties may contact me at megamarc1@aol.com

Dr. John Cannell (the lead author of the paper) and I have nearly finished a book entitled "Quicker, Stronger, Faster with vitamin D." It will expatiate on the materials in the paper and furnish additional information.

In the meantime, all of you who are athletes should have your vitamin D levels assessed. If you are deficient, a bit more sunshine and vitamin D may just help you win your next competition.

Reference:
(1) Cannell JJ, Hollis BW, Sorenson MB, Taft TN, Anderson JJ. Athletic Performance and Vitamin D. Med Sci Sports Exerc. 2009 Apr 3. [Epub ahead of print]

Tuesday, April 28, 2009

Vitamin D: Our best protection against swine flu?

A headline reads, “Officials Race to Contain Swine Flu.” Another says, “CDC: Swine Flu Cases In NYC Rise To 45.” Still another screams, “Swine flu spreads to Middle East, Asia-Pacific.”

Strangely, there are no headlines that read, “Government delivers vitamin D3 to the masses to thwart flu pandemic.” It is worrisome that the least expensive, most effective therapy for flu prevention is hardly ever mentioned, probably because it sells no expensive drugs. For those who fear the flu and seek the best method of protection against it, I refer them to my earlier blogs on the subject in hopes that the information may ease apprehensions and save a few lives along the way. Here are four posts that explain the critical importance of high vitamin D levels to prevent flu.

http://drsorenson.blogspot.com/2008/12/vitamin-d-immune-system-and-yearly.html

http://drsorenson.blogspot.com/2008/12/vitamin-d-flu-and-immune-system-part-2.html


http://drsorenson.blogspot.com/2009/02/most-popular-flu-drug-is-now-99.html

http://drsorenson.blogspot.com/2009/02/killer-virus-grips-britain-and-so-does.html

I implore you to read the posts and the references that accompany them. The information could save your life!

Friday, April 17, 2009

NIF is back. The sunlight and vitamin D health resort will open in June!

Come learn about vitamin D, sunlight, and health while you lose weight, lower cholesterol, lower blood pressure and blood sugar and improve your vitality and wellbeing. Most people are severely vitamin D-deficient, and the education they receive may save their lives.

My wife, Vicki, and I previously owned one of the most popular destination health resorts (or “spas”) in the world, known as National Institute of Fitness (NIF). We are now opening another at our Nevada ranch, located next to Great Basin National Park. We will have one of the lowest prices in the industry and in addition to our work with nutrition and exercise, our education will also concentrate on the health benefits of vitamin D. We will still be known as NIF (Nevada Institute of Fitness).

Here are some of the results our guests experienced at our first resort:
During our 20+ years at NIF, our clients lost 110 tons of fat, two thirds of diabetic guests were free of all medication in less than two weeks, and many others recovered from high cholesterol, lupus, arthritis, migraines, hypertension, angina, arthritis and allergies. The institute was consistently ranked as one of the world’s best destination spas and was featured in major newspaper articles in the New York Times as well as other papers throughout the US and in Japan and Singapore.

You can learn more about our operation at http://nifathcr.com/

Wednesday, April 8, 2009

Do you suffer from rheumatoid arthritis (RA)? Can vitamin D help?

Both dietary and supplemental vitamin D reduce the risk of RA, which is an autoimmune disease—a disease in which the body’s immune system attacks its own tissue. In a study of 29,000 women, those who ranked in the top third of vitamin D consumption had one-third less risk of RA.[1] It is likely that a greater vitamin D intake would have produced much better results, since it is virtually impossible to ingest sufficient vitamin D from food and multivitamins.

In studies performed on mice, vitamin D was shown to inhibit the progression of rheumatoid arthritis and minimize or prevent symptoms.[2] The same is true in humans. In subjects diagnosed with a form of the disease known as inflammatory arthritis, the lower the vitamin D levels are, the higher is the disease activity.[3] Vitamin D's anti-inflammatory properties and its ability to reduce the autoimmune response are likely responsible for the improvement in RA.[4]

Investigations also find that RA is more common in winter, consistent with the idea that vitamin D is a major factor in reducing the risk.[5] In a report from researchers in Ireland, it was shown that 70% of patients had low vitamin D levels and that 26% were severely deficient.[6] However, in that report, 21 ng/ml was considered as the deficiency level and 10 as the severe deficiency level. A level of 21 is dangerously deficient. The ideal level of vitamin D is 50-60 ng/ml. Using those numbers, it is likely that all of these patients ranged between deficient and severely deficient.

In our health institute/resort, we observed that guests with arthritis often regained full range of motion in their joints from a week to a month after beginning a program. I assumed that our anti-inflammatory vegetarian nutrition was responsible for the positive results. Now I realize that many of the benefits came from sunlight exposure during outdoor exercise.

RA prevention and relief are two more reasons to obtain regular, non-burning sunlight exposure. Remember that sunscreens can prevent 99% of vitamin D production by the skin.

[1] Merlino, L. et al. Vitamin D intake is inversely associated with rheumatoid arthritis: Results from the Iowa Women’s Health Study. Arthritis & Rheumatism 2004;50:72-77.
[2] Cantorna, M. et al. 1,25-Dihydroxycholecalciferol inhibits the progression of arthritis in murine models of human arthritis. J Nutr1998;128:68-72.
[3] Patel, S. et al. Serum vitamin D metabolite levels may be inversely associated with current disease activity in patients with early inflammatory polyarthritis. Arthritis Rheum 2007;56;2143-49.
[4] Cutolo, M. et al. Vitamin D in rheumatoid arthritis. Autoimmune Rev 2007;7:59-64.
[5] Cutolo, M. et al. Circannual vitamin D serum levels and disease activity in rheumatoid arthritis: Northern versus Southern Europe. Clin Exp Rheumatol 2006;24:702-4.
[6] Haroon, M. Report to European Union League Against Rheumatism , June 13, 2008.